During his playing days at the University of Colorado, Crosby was widely considered the best kicker in college football. Crosby was a unanimous selection as a First Team All American by the Associated Press, the Football Writers Association of America, The Sporting News, and Walter Camp Football Foundation for the 2005 NCAA Division I-A football season. 

Mason Crosby was chosen by the Green Bay Packers with the 19th pick of the sixth round of the 2007 NFL Draft.

Crosby is the first player in NFL history to kick a 50-yard field goal and a game-winning field goal with under a minute remaining in his NFL debut.

On July 27, 2011, the Packers re-signed Crosby to a 5-year deal.